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PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via act...

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via act...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68638749

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP

About this item

Full title

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2005-09, Vol.24 (43), p.6465-6481

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Protein kinase B (PKB/Akt) has been shown to play a role in protection from apoptosis, cell proliferation and cell growth. It is also involved in mediating the effects of insulin, such as lipogenesis, glucose uptake and conversion of glucose into fatty acids and cholesterol. Sterol-regulatory element binding proteins (SREBPs) are the major transcri...

Alternative Titles

Full title

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68638749

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68638749

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1208802

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