The melanocyte differentiation program predisposes to metastasis after neoplastic transformation
The melanocyte differentiation program predisposes to metastasis after neoplastic transformation
About this item
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Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
The aggressive clinical behavior of melanoma suggests that the developmental origins of melanocytes in the neural crest might be relevant to their metastatic propensity. Here we show that primary human melanocytes, transformed using a specific set of introduced genes, form melanomas that frequently metastasize to multiple secondary sites, whereas h...
Alternative Titles
Full title
The melanocyte differentiation program predisposes to metastasis after neoplastic transformation
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Record Identifier
TN_cdi_proquest_miscellaneous_68649060
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68649060
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng1634
