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Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9

Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68753185

Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9

About this item

Full title

Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9

Publisher

London: Nature Publishing Group UK

Journal title

Nature, 2006-08, Vol.442 (7104), p.818-822

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Identity of cancer stem cells
Cancer is thought to arise either from normal tissue cells or committed progenitors. A key question is how in the latter case cancer stem cells with the ability to self-renew — a property lacking in progenitor cells — can arise. A population of mouse leukaemia stem cells capable of initiating leukaemia when as few a...

Alternative Titles

Full title

Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68753185

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68753185

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687,1476-4679

DOI

10.1038/nature04980

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