Mechanisms of Disease: histone modifications in Huntington's disease
Mechanisms of Disease: histone modifications in Huntington's disease
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Transcriptional dysregulation is proposed to have an important role in the pathogenesis of Huntington's disease, and recent studies have implicated abnormal modifications of histone proteins in this process. Sadri-Vakili and Jang-Ho Cha review human and animal studies that have provided evidence for such a mechanism, and discuss the therapeutic pot...
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Full title
Mechanisms of Disease: histone modifications in Huntington's disease
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TN_cdi_proquest_miscellaneous_68785551
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68785551
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ISSN
1745-834X
E-ISSN
1745-8358
DOI
10.1038/ncpneuro0199
