Pharmacologic Blockade of Angiopoietin-2 Is Efficacious against Model Hemangiomas in Mice
Pharmacologic Blockade of Angiopoietin-2 Is Efficacious against Model Hemangiomas in Mice
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Author / Creator
Perry, Betsy N. , Govindarajan, Baskaran , Bhandarkar, Sulochana S. , Knaus, Ulla G. , Valo, Monika , Sturk, Celina , Carrillo, Carol O. , Sohn, Allie , Cerimele, Francesca , Dumont, Dan , Losken, Albert , Williams, Joseph , Brown, Lawrence F. , Tan, Xiaolian , Ioffe, Ella , Yancopoulos, George D. and Arbiser, Jack L.
Publisher
Danvers, MA: Elsevier Inc
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Language
English
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Publisher
Danvers, MA: Elsevier Inc
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Contents
Hemangioma of infancy is the most common neoplasm of childhood. While hemangiomas are classic examples of angiogenesis, the angiogenic factors responsible for hemangiomas are not fully understood. Previously, we demonstrated that malignant endothelial tumors arise in the setting of autocrine loops involving vascular endothelial growth factor (VEGF)...
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Full title
Pharmacologic Blockade of Angiopoietin-2 Is Efficacious against Model Hemangiomas in Mice
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Record Identifier
TN_cdi_proquest_miscellaneous_68872359
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68872359
Other Identifiers
ISSN
0022-202X
E-ISSN
1523-1747
DOI
10.1038/sj.jid.5700413
