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Reference EntriesFull Text
Yancopoulos, George D
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: WIE-ZYW, 2022, p.12588-12588
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Yancopoulos, George D
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: WIL-ZYW, 2021, p.12556-12556
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Newsletter articlesFull Text
INTERNATIONAL PATENT: REGENERON PHARMACEUTICALS, INC., YANCOPOULOS, GEORGE, D. FILES APPLICATION FOR "ANTI-FACTOR XII/XIIA ANTIBODIES AND USES THEREOF"
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2025
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ArticlesPeer ReviewedFull Text
Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma
Author / Creator:Rabe, Klaus F ; Nair, Parameswaran ; Brusselle, Guy ; Maspero, Jorge F ; Castro, Mario ; Sher, Lawrence ; Zhu, Hongjie ; Hamilton, Jennifer D ; Swanson, Brian N ; Khan, Asif ; Chao, Jingdong ; Staudinger, Heribert ; Pirozzi, Gianluca ; Antoni, Christian ; Amin, Nikhil ; Ruddy, Marcella ; Akinlade, Bolanle ; Graham, Neil M.H ; Stahl, Neil ; Yancopoulos, George D ; Teper, Ariel
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2018-06, Vol.378 (26), p.2475-2485
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Cemiplimab plus chemotherapy versus chemotherapy alone in non-small cell lung cancer: a randomized, controlled, double-blind phase 3 trial
Author / Creator:Gogishvili, Miranda ; Melkadze, Tamar ; Makharadze, Tamta ; Giorgadze, Davit ; Dvorkin, Mikhail ; Penkov, Konstantin ; Laktionov, Konstantin ; Nemsadze, Gia ; Nechaeva, Marina ; Rozhkova, Irina ; Kalinka, Ewa ; Gessner, Christian ; Moreno-Jaime, Brizio ; Passalacqua, Rodolfo ; Li, Siyu ; McGuire, Kristina ; Kaul, Manika ; Paccaly, Anne ; Quek, Ruben G. W. ; Gao, Bo ; Seebach, Frank ; Weinreich, David M. ; Yancopoulos, George D. ; Lowy, Israel ; Gullo, Giuseppe ; Rietschel, Petra
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2022-11, Vol.28 (11), p.2374-2380
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ArticlesPeer ReviewedFull Text
Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-...
Author / Creator:Wenzel, Sally, Prof ; Castro, Mario, MD ; Corren, Jonathan, MD ; Maspero, Jorge, MD ; Wang, Lin, PhD ; Zhang, Bingzhi, PhD ; Pirozzi, Gianluca, MD ; Sutherland, E Rand, MD ; Evans, Robert R, PharmD ; Joish, Vijay N, PhD ; Eckert, Laurent, PhD ; Graham, Neil M H, MD ; Stahl, Neil, PhD ; Yancopoulos, George D, MD ; Louis-Tisserand, Mariana, MD ; Teper, Ariel, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-07, Vol.388 (10039), p.31-44
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ArticlesPeer ReviewedFull Text
Cemiplimab in locally advanced cutaneous squamous cell carcinoma: results from an open-label, phase 2, single-arm trial
Author / Creator:Migden, Michael R, Prof ; Khushalani, Nikhil I, Prof ; Chang, Anne Lynn S, MD ; Lewis, Karl D, MD ; Schmults, Chrysalyne D, MD ; Hernandez-Aya, Leonel, MD ; Meier, Friedegund, Prof ; Schadendorf, Dirk, Prof ; Guminski, Alexander, MD ; Hauschild, Axel, Prof ; Wong, Deborah J, MD ; Daniels, Gregory A, Prof ; Berking, Carola, Prof ; Jankovic, Vladimir, MD ; Stankevich, Elizabeth, BS ; Booth, Jocelyn, MBA ; Li, Siyu, PhD ; Weinreich, David M, MD ; Yancopoulos, George D, MD ; Lowy, Israel, MD ; Fury, Matthew G, MD ; Rischin, Danny, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2020-02, Vol.21 (2), p.294-305
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ArticlesPeer ReviewedFull Text
ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia
Author / Creator:Gaudet, Daniel ; Gipe, Daniel A ; Pordy, Robert ; Ahmad, Zahid ; Cuchel, Marina ; Shah, Prediman K ; Chyu, Kuang-Yuh ; Sasiela, William J ; Chan, Kuo-Chen ; Brisson, Diane ; Khoury, Etienne ; Banerjee, Poulabi ; Gusarova, Viktoria ; Gromada, Jesper ; Stahl, Neil ; Yancopoulos, George D ; Hovingh, G. Kees
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-07, Vol.377 (3), p.296-297
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ArticlesPeer ReviewedFull Text
Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab
Author / Creator:Papadopoulos, Nicholas ; Martin, Joel ; Ruan, Qin ; Rafique, Ashique ; Rosconi, Michael P. ; Shi, Ergang ; Pyles, Erica A. ; Yancopoulos, George D. ; Stahl, Neil ; Wiegand, Stanley J.
Publisher:Dordrecht: Springer Netherlands
Journal title:Angiogenesis (London), 2012-06, Vol.15 (2), p.171-185
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ArticlesPeer ReviewedFull Text
Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol
Author / Creator:Stein, Evan A ; Mellis, Scott ; Yancopoulos, George D ; Stahl, Neil ; Logan, Douglas ; Smith, William B ; Lisbon, Eleanor ; Gutierrez, Maria ; Webb, Cheryle ; Wu, Richard ; Du, Yunling ; Kranz, Therese ; Gasparino, Evelyn ; Swergold, Gary D
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2012-03, Vol.366 (12), p.1108-1118
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ArticlesPeer ReviewedFull Text
Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes
Author / Creator:Macdonald, Lynn E. ; Karow, Margaret ; Stevens, Sean ; Auerbach, Wojtek ; Poueymirou, William T. ; Yasenchak, Jason ; Frendewey, David ; Valenzuela, David M. ; Giallourakis, Cosmas C. ; Alt, Frederick W. ; Yancopoulos, George D. ; Murphy, Andrew J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (14), p.5147-5152
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ArticlesPeer ReviewedFull Text
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
Author / Creator:Huber, Samuel ; Gagliani, Nicola ; Zenewicz, Lauren A. ; Huber, Francis J. ; Bosurgi, Lidia ; Hu, Bo ; Hedl, Matija ; Zhang, Wei ; O’Connor, William ; Murphy, Andrew J. ; Valenzuela, David M. ; Yancopoulos, George D. ; Booth, Carmen J. ; Cho, Judy H. ; Ouyang, Wenjun ; Abraham, Clara ; Flavell, Richard A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-11, Vol.491 (7423), p.259-263
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ArticlesPeer ReviewedFull Text
Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice
Author / Creator:Murphy, Andrew J. ; Macdonald, Lynn E. ; Stevens, Sean ; Karow, Margaret ; Dore, Anthony T. ; Pobursky, Kevin ; Huang, Tammy T. ; Poueymirou, William T. ; Esau, Lakeisha ; Meola, Melissa ; Mikulka, Warren ; Krueger, Pamela ; Fairhurst, Jeanette ; Valenzuela, David M. ; Papadopoulos, Nicholas ; Yancopoulos, George D.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (14), p.5153-5158
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ArticlesPeer ReviewedFull Text
Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations
Author / Creator:Deng, Kai ; Pertea, Mihaela ; Rongvaux, Anthony ; Wang, Leyao ; Durand, Christine M. ; Ghiaur, Gabriel ; Lai, Jun ; McHugh, Holly L. ; Hao, Haiping ; Zhang, Hao ; Margolick, Joseph B. ; Gurer, Cagan ; Murphy, Andrew J. ; Valenzuela, David M. ; Yancopoulos, George D. ; Deeks, Steven G. ; Strowig, Till ; Kumar, Priti ; Siliciano, Janet D. ; Salzberg, Steven L. ; Flavell, Richard A. ; Shan, Liang ; Siliciano, Robert F.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-01, Vol.517 (7534), p.381-385
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ArticlesPeer ReviewedFull Text
Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial
Author / Creator:Thaçi, Diamant, Prof ; Simpson, Eric L, MD ; Beck, Lisa A, Prof ; Bieber, Thomas, Prof ; Blauvelt, Andrew, MD ; Papp, Kim, MD ; Soong, Weily, MD ; Worm, Margitta, Univ-Prof ; Szepietowski, Jacek C, Prof ; Sofen, Howard, MD ; Kawashima, Makoto, Prof ; Wu, Richard, PhD ; Weinstein, Steven P, MD ; Graham, Neil M H, MD ; Pirozzi, Gianluca, MD ; Teper, Ariel, MD ; Sutherland, E Rand, MD ; Mastey, Vera, MS ; Stahl, Neil, PhD ; Yancopoulos, George D, MD ; Ardeleanu, Marius, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-01, Vol.387 (10013), p.40-52
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ArticlesPeer ReviewedFull Text
Use of the Fluidigm C1 platform for RNA sequencing of single mouse pancreatic islet cells
Author / Creator:Xin, Yurong ; Kim, Jinrang ; Ni, Min ; Wei, Yi ; Okamoto, Haruka ; Lee, Joseph ; Adler, Christina ; Cavino, Katie ; Murphy, Andrew J. ; Yancopoulos, George D. ; Lin, Hsin Chieh ; Gromada, Jesper
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (12), p.3293-3298
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ArticlesPeer ReviewedFull Text
Humanized mouse model supports development, function, and tissue residency of human natural killer cells
Author / Creator:Herndler-Brandstetter, Dietmar ; Shan, Liang ; Yao, Yi ; Stecher, Carmen ; Plajer, Valerie ; Lietzenmayer, Melanie ; Strowig, Till ; de Zoete, Marcel R. ; Palm, Noah W. ; Chen, Jie ; Blish, Catherine A. ; Frleta, Davor ; Gurer, Cagan ; Macdonald, Lynn E. ; Murphy, Andrew J. ; Yancopoulos, George D. ; Montgomery, Ruth R. ; Flavell, Richard A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (45), p.E9626-E9634
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ArticlesPeer ReviewedFull Text
Infections in Dupilumab Clinical Trials in Atopic Dermatitis: A Comprehensive Pooled Analysis
Author / Creator:Eichenfield, Lawrence F. ; Bieber, Thomas ; Beck, Lisa A. ; Simpson, Eric L. ; Thaçi, Diamant ; de Bruin-Weller, Marjolein ; Deleuran, Mette ; Silverberg, Jonathan I. ; Ferrandiz, Carlos ; Fölster-Holst, Regina ; Chen, Zhen ; Graham, Neil M. H. ; Pirozzi, Gianluca ; Akinlade, Bolanle ; Yancopoulos, George D. ; Ardeleanu, Marius
Publisher:Cham: Springer International Publishing
Journal title:American journal of clinical dermatology, 2019-06, Vol.20 (3), p.443-456
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ArticlesPeer ReviewedFull Text
Activin A more prominently regulates muscle mass in primates than does GDF8
Author / Creator:Latres, Esther ; Mastaitis, Jason ; Fury, Wen ; Miloscio, Lawrence ; Trejos, Jesus ; Pangilinan, Jeffrey ; Okamoto, Haruka ; Cavino, Katie ; Na, Erqian ; Papatheodorou, Angelos ; Willer, Tobias ; Bai, Yu ; Hae Kim, Jee ; Rafique, Ashique ; Jaspers, Stephen ; Stitt, Trevor ; Murphy, Andrew J. ; Yancopoulos, George D. ; Gromada, Jesper
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-04, Vol.8 (1), p.15153-15153, Article 15153
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ArticlesPeer ReviewedFull Text
Glucagon contributes to liver zonation
Author / Creator:Cheng, Xiping ; Kim, Sun Y. ; Okamoto, Haruka ; Xin, Yurong ; Yancopoulos, George D. ; Murphy, Andrew J. ; Gromada, Jesper
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (17), p.E4111-E4119
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Yancopoulos, George D

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Yancopoulos, George D

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INTERNATIONAL PATENT: REGENERON PHARMACEUTICALS, INC., YANCOPOULOS, GEORGE, D. FILES APPLICATION FOR "ANTI-FACTOR XII/XIIA ANTIBODIES AND USES THEREOF"

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Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma

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Cemiplimab plus chemotherapy versus chemotherapy alone in non-small cell lung cancer: a randomized, controlled, double-blind phase 3 trial

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Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-...

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Cemiplimab in locally advanced cutaneous squamous cell carcinoma: results from an open-label, phase 2, single-arm trial

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ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia

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Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

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Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol

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Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes

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IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

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Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice

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Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

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Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial

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Use of the Fluidigm C1 platform for RNA sequencing of single mouse pancreatic islet cells

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Humanized mouse model supports development, function, and tissue residency of human natural killer cells

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Infections in Dupilumab Clinical Trials in Atopic Dermatitis: A Comprehensive Pooled Analysis

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Activin A more prominently regulates muscle mass in primates than does GDF8

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Glucagon contributes to liver zonation

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