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Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis

Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68936187

Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis

About this item

Full title

Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis

Publisher

Netherlands: Springer Nature B.V

Journal title

Molecular and cellular biochemistry, 2007-01, Vol.295 (1-2), p.85-92

Language

English

Formats

Publication information

Publisher

Netherlands: Springer Nature B.V

More information

Scope and Contents

Contents

Proline oxidase (POX), a mitochondrial inner-membrane protein, catalyzes the rate-limiting oxidation of proline to pyrroline- 5-carboxylate (P5C). Previously we showed that overexpression of POX is associated with generation of reactive oxygen species (ROS) and apoptosis in POX-inducible colorectal cancer cells, DLD-1.POX. We also showed expression...

Alternative Titles

Full title

Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_68936187

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68936187

Other Identifiers

ISSN

0300-8177

E-ISSN

1573-4919

DOI

10.1007/s11010-006-9276-6

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