Androgen receptor decoy molecules block the growth of prostate cancer
Androgen receptor decoy molecules block the growth of prostate cancer
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
The androgen receptor (AR) is activated by both ligand-dependent and -independent mechanisms. Current therapies for prostate cancer target the ligand-binding domain in the C terminus of the AR. However, ligand-independent activation of the AR occurs by the N-terminal domain (NTD), making the NTD a potential novel target for the treatment of hormone...
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Full title
Androgen receptor decoy molecules block the growth of prostate cancer
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TN_cdi_proquest_miscellaneous_68945712
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68945712
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0606718104