Angiopoietin-2 Functions as an Autocrine Protective Factor in Stressed Endothelial Cells
Angiopoietin-2 Functions as an Autocrine Protective Factor in Stressed Endothelial Cells
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Angiopoietin (Ang)-2, a context-dependent agonist/antagonist for the vascular-specific Tie2 receptor, is highly expressed by endothelial cells at sites of normal and pathologic angiogenesis. One prevailing model suggests that in these settings, Ang-2 acts as an autocrine Tie2 blocker, inhibiting the stabilizing influence of the Tie2 activator Ang-1...
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Full title
Angiopoietin-2 Functions as an Autocrine Protective Factor in Stressed Endothelial Cells
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TN_cdi_proquest_miscellaneous_68969019
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_68969019
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0607538103
