Odorant Receptor-Derived cAMP Signals Direct Axonal Targeting
Odorant Receptor-Derived cAMP Signals Direct Axonal Targeting
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Washington, DC: American Association for the Advancement of Science
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Contents
In mammals, odorant receptors (ORs) direct the axons of olfactory sensory neurons (OSNs) toward targets in the olfactory bulb. We show that cyclic adenosine monophosphate (cAMP) signals that regulate the expression of axon guidance molecules are essential for the OR-instructed axonal projection. Genetic manipulations of ORs, stimulatory G protein,...
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Full title
Odorant Receptor-Derived cAMP Signals Direct Axonal Targeting
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TN_cdi_proquest_miscellaneous_69003537
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69003537
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1131794
