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Lack of Nidogen-1 and -2 Prevents Basement Membrane Assembly in Skin-Organotypic Coculture

Lack of Nidogen-1 and -2 Prevents Basement Membrane Assembly in Skin-Organotypic Coculture

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69009783

Lack of Nidogen-1 and -2 Prevents Basement Membrane Assembly in Skin-Organotypic Coculture

About this item

Full title

Lack of Nidogen-1 and -2 Prevents Basement Membrane Assembly in Skin-Organotypic Coculture

Publisher

Danvers, MA: Elsevier Inc

Journal title

Journal of investigative dermatology, 2007-03, Vol.127 (3), p.545-554

Language

English

Formats

Publication information

Publisher

Danvers, MA: Elsevier Inc

More information

Scope and Contents

Contents

Nidogens are considered as classical linkers joining laminin and collagen IV networks in basement membranes (BMs); however, recent genetic approaches have suggested that nidogens function in a tissue-specific and developmental context. Thus, in mice lacking both nidogen-1 and -2 heart and lung were severely affected, causing neonatal death. Further...

Alternative Titles

Full title

Lack of Nidogen-1 and -2 Prevents Basement Membrane Assembly in Skin-Organotypic Coculture

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69009783

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69009783

Other Identifiers

ISSN

0022-202X

E-ISSN

1523-1747

DOI

10.1038/sj.jid.5700562

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