Antisense oligonucleotides targeting midkine inhibit tumor growth in an in situ human hepatocellular...
Antisense oligonucleotides targeting midkine inhibit tumor growth in an in situ human hepatocellular carcinoma model
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United States: Nature Publishing Group
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English
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United States: Nature Publishing Group
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Aim: To evaluate the in vivo antitumor effects of antisense oligonucleotides targeting midldne (MK-AS). Methods: An in situ human hepatocellular carcinoma (HCC) model was established in mice livers orthotopically. The MK-AS and 5- fluorouracil (5-Fu) were administered intravenously. The tumor sizes and plasma alpha-fetoprotein (AFP) were measured b...
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Antisense oligonucleotides targeting midkine inhibit tumor growth in an in situ human hepatocellular carcinoma model
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TN_cdi_proquest_miscellaneous_69018905
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69018905
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ISSN
1671-4083
E-ISSN
1745-7254
DOI
10.1111/j.1745-7254.2007.00532.x