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Antisense oligonucleotides targeting midkine inhibit tumor growth in an in situ human hepatocellular...

Antisense oligonucleotides targeting midkine inhibit tumor growth in an in situ human hepatocellular...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69018905

Antisense oligonucleotides targeting midkine inhibit tumor growth in an in situ human hepatocellular carcinoma model

About this item

Full title

Antisense oligonucleotides targeting midkine inhibit tumor growth in an in situ human hepatocellular carcinoma model

Publisher

United States: Nature Publishing Group

Journal title

Acta pharmacologica Sinica, 2007-03, Vol.28 (3), p.453-457

Language

English

Formats

Publication information

Publisher

United States: Nature Publishing Group

More information

Scope and Contents

Contents

Aim: To evaluate the in vivo antitumor effects of antisense oligonucleotides targeting midldne (MK-AS). Methods: An in situ human hepatocellular carcinoma (HCC) model was established in mice livers orthotopically. The MK-AS and 5- fluorouracil (5-Fu) were administered intravenously. The tumor sizes and plasma alpha-fetoprotein (AFP) were measured b...

Alternative Titles

Full title

Antisense oligonucleotides targeting midkine inhibit tumor growth in an in situ human hepatocellular carcinoma model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69018905

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69018905

Other Identifiers

ISSN

1671-4083

E-ISSN

1745-7254

DOI

10.1111/j.1745-7254.2007.00532.x

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