The Salvador–Warts–Hippo pathway — an emerging tumour-suppressor network
The Salvador–Warts–Hippo pathway — an emerging tumour-suppressor network
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
The Salvador–Warts–Hippo (SWH) pathway controls organ size by modulating cell growth, proliferation and apoptosis.
Deregulation of this pathway in
Drosophila melanogaster
leads to dramatic increases in organ size.
Proteins predicted to function in the SWH pathway include the cadherin Fat, the band 4.1 proteins Expanded and...
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Full title
The Salvador–Warts–Hippo pathway — an emerging tumour-suppressor network
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TN_cdi_proquest_miscellaneous_69037076
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69037076
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc2070
