Proliferating Cells Express mRNAs with Shortened 3′ Untranslated Regions and Fewer MicroRNA Target S...
Proliferating Cells Express mRNAs with Shortened 3′ Untranslated Regions and Fewer MicroRNA Target Sites
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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Messenger RNA (mRNA) stability, localization, and translation are largely determined by sequences in the 3′ untranslated region (3′UTR). We found a conserved increase in expression of mRNAs terminating at upstream polyadenylation sites after activation of primary murine CD4⁺ T lymphocytes. This program, resulting in shorter 3′UTRs, is a characteris...
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Proliferating Cells Express mRNAs with Shortened 3′ Untranslated Regions and Fewer MicroRNA Target Sites
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TN_cdi_proquest_miscellaneous_69228709
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69228709
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1155390
