Interferon regulatory factor 4 differentially regulates the production of Th2 cytokines in naïve vs....
Interferon regulatory factor 4 differentially regulates the production of Th2 cytokines in naïve vs. effector/memory CD4⁺ T cells
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Interferon regulatory factor (IRF) 4 is a member of the IRF family of transcription factors and plays critical roles in the development of CD4⁺ T cells into Th2 and Th17 cells. Using the infection model of Nippostrongyrus brasiliensis, we have confirmed the critical roles of IRF-4 in Th2 development in vivo by using IRF-4⁻/⁻ BALB/c mice. However, n...
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Full title
Interferon regulatory factor 4 differentially regulates the production of Th2 cytokines in naïve vs. effector/memory CD4⁺ T cells
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TN_cdi_proquest_miscellaneous_69675310
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69675310
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0803171105
