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α-Toxin Facilitates the Generation of CXC Chemokine Gradients and Stimulates Neutrophil Homing in St...

α-Toxin Facilitates the Generation of CXC Chemokine Gradients and Stimulates Neutrophil Homing in St...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69719254

α-Toxin Facilitates the Generation of CXC Chemokine Gradients and Stimulates Neutrophil Homing in Staphylococcus aureus Pneumonia

About this item

Full title

α-Toxin Facilitates the Generation of CXC Chemokine Gradients and Stimulates Neutrophil Homing in Staphylococcus aureus Pneumonia

Publisher

Chicago, IL: The University of Chicago Press

Journal title

The Journal of infectious diseases, 2008-11, Vol.198 (10), p.1529-1535

Language

English

Formats

Publication information

Publisher

Chicago, IL: The University of Chicago Press

More information

Scope and Contents

Contents

Background. Staphylococcus aureus α-toxin is a major virulence factor, but its mechanism of action in vivo is incompletely understood. Methods. We examined the role of α-toxin in S. aureus pneumonia using the mouse model of intranasal lung infection with S. aureus strain 8325–4 (hla+ S. aureus) and an α-toxin-deficient mutant strain made on the 832...

Alternative Titles

Full title

α-Toxin Facilitates the Generation of CXC Chemokine Gradients and Stimulates Neutrophil Homing in Staphylococcus aureus Pneumonia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69719254

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69719254

Other Identifiers

ISSN

0022-1899

E-ISSN

1537-6613

DOI

10.1086/592758

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