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Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69749942

Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

About this item

Full title

Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2008-11, Vol.10 (11), p.1324-1332

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Stress-induced MAPK-dependent apoptosis is inhibited by the formation of stress granules, which sequester and inactivate the MTK1 activator RACK1.
When confronted with environmental stress, cells either activate defence mechanisms to survive, or initiate apoptosis, depending on the type of stress. Certain types of stress, such as hypoxia, heatsh...

Alternative Titles

Full title

Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_69749942

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_69749942

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/ncb1791

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