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InSite: a computational method for identifying protein-protein interaction binding sites on a proteo...

InSite: a computational method for identifying protein-protein interaction binding sites on a proteo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70063914

InSite: a computational method for identifying protein-protein interaction binding sites on a proteome-wide scale

About this item

Full title

InSite: a computational method for identifying protein-protein interaction binding sites on a proteome-wide scale

Publisher

England: BioMed Central Ltd

Journal title

Genome Biology (Online Edition), 2007-09, Vol.8 (9), p.R192-1673, Article R192

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

We propose InSite, a computational method that integrates high-throughput protein and sequence data to infer the specific binding regions of interacting protein pairs. We compared our predictions with binding sites in Protein Data Bank and found significantly more binding events occur at sites we predicted. Several regions containing disease-causin...

Alternative Titles

Full title

InSite: a computational method for identifying protein-protein interaction binding sites on a proteome-wide scale

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70063914

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70063914

Other Identifiers

ISSN

1474-760X

E-ISSN

1474-760X

DOI

10.1186/gb-2007-8-9-r192

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