Structural basis for the function and inhibition of an influenza virus proton channel
Structural basis for the function and inhibition of an influenza virus proton channel
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Influenza changes channels
Until recently, the pH-gated proton channel of influenza A virus, M2, was effectively targeted by amantadine-based antivirals, but resistance to these drugs is now widespread. Two groups now present structural studies of M2 proton channel. Jason Schnell and James Chou determine the structure of a 38-residue segment of...
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Structural basis for the function and inhibition of an influenza virus proton channel
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TN_cdi_proquest_miscellaneous_70253754
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70253754
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0028-0836
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1476-4687,1476-4679
DOI
10.1038/nature06528