Protein kinase A suppresses the differentiation of 3T3-L1 preadipocytes
Protein kinase A suppresses the differentiation of 3T3-L1 preadipocytes
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Author / Creator
Li, Fuqiang , Wang, Dongmei , Zhou, Yiran , Zhou, Bo , Yang, Yanan , Chen, Hehua and Song, Jianguo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
cAMP and protein kinase A (PKA) are widely known as signaling molecules that are important for the induction of adipogenesis. Here we show that a strong increase in the amount of cAMP inhibits the adipogenesis of 3T3-L1 fibroblast cells. Stimulation of PKA activity suppresses adipogenesis and, in contrast, inhibition of PKA activity markedly accele...
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Full title
Protein kinase A suppresses the differentiation of 3T3-L1 preadipocytes
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Record Identifier
TN_cdi_proquest_miscellaneous_70265261
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70265261
Other Identifiers
ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2008.12