Zebrafish pten genes have overlapping and non-redundant functions in tumorigenesis and embryonic dev...
Zebrafish pten genes have overlapping and non-redundant functions in tumorigenesis and embryonic development
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In human cancer, PTEN (Phosphatase and TENsin homolog on chromosome 10, also referred to as MMAC1 and TEP1) is a frequently mutated tumor suppressor gene. We have used the zebrafish as a model to investigate the role of Pten in embryonic development and tumorigenesis. The zebrafish genome encodes two
pten
genes,
ptena
and
ptenb
....
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Zebrafish pten genes have overlapping and non-redundant functions in tumorigenesis and embryonic development
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TN_cdi_proquest_miscellaneous_70298663
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70298663
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1210730
