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Asymmetric T Lymphocyte Division in the Initiation of Adaptive Immune Responses

Asymmetric T Lymphocyte Division in the Initiation of Adaptive Immune Responses

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70305307

Asymmetric T Lymphocyte Division in the Initiation of Adaptive Immune Responses

About this item

Full title

Asymmetric T Lymphocyte Division in the Initiation of Adaptive Immune Responses

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2007-03, Vol.315 (5819), p.1687-1691

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

A hallmark of mammalian immunity is the heterogeneity of cell fate that exists among pathogen-experienced lymphocytes. We show that a dividing T lymphocyte initially responding to a microbe exhibits unequal partitioning of proteins that mediate signaling, cell fate specification, and asymmetric cell division. Asymmetric segregation of determinants...

Alternative Titles

Full title

Asymmetric T Lymphocyte Division in the Initiation of Adaptive Immune Responses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70305307

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70305307

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1139393

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