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Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability

Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70327046

Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability

About this item

Full title

Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability

Publisher

England: Nature Publishing Group

Journal title

Nature reviews. Cancer, 2008-03, Vol.8 (3), p.180-192

Language

English

Formats

Publication information

Publisher

England: Nature Publishing Group

More information

Scope and Contents

Contents

Areas of hypoxic tumour tissue are known to be resistant to treatment and are associated with a poor clinical prognosis. There are several reasons why this might be, including the capacity of hypoxia to drive genomic instability and alter DNA damage repair pathways. Significantly, current models fail to distinguish between the complexities of the h...

Alternative Titles

Full title

Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70327046

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70327046

Other Identifiers

ISSN

1474-175X

E-ISSN

1474-1768

DOI

10.1038/nrc2344

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