Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability
Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability
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Publisher
England: Nature Publishing Group
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Language
English
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Publisher
England: Nature Publishing Group
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Contents
Areas of hypoxic tumour tissue are known to be resistant to treatment and are associated with a poor clinical prognosis. There are several reasons why this might be, including the capacity of hypoxia to drive genomic instability and alter DNA damage repair pathways. Significantly, current models fail to distinguish between the complexities of the h...
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Full title
Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability
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TN_cdi_proquest_miscellaneous_70327046
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70327046
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc2344