Maintaining serum response factor activity in the older heart equal to that of the young adult is as...
Maintaining serum response factor activity in the older heart equal to that of the young adult is associated with better cardiac response to isoproterenol stress
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Germany: Springer Nature B.V
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Language
English
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Germany: Springer Nature B.V
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To understand the effect of transcription regulation in modulating cardiac aging, we sought to study the role of serum response factor (SRF), a key transcription factor in the heart that is normally increased with senescence and also in congestive heart failure. A Tet-Off gene expression system was used for cardiac-specific over-expression of a mut...
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Maintaining serum response factor activity in the older heart equal to that of the young adult is associated with better cardiac response to isoproterenol stress
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TN_cdi_proquest_miscellaneous_70363760
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70363760
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ISSN
0300-8428
E-ISSN
1435-1803
DOI
10.1007/s00395-006-0634-z
