Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33
Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33
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Author / Creator
Gold, Bert , Kirchhoff, Tomas , Stefanov, Stefan , Lautenberger, James , Viale, Agnes , Garber, Judy , Friedman, Eitan , Narod, Steven , Olshen, Adam B , Gregersen, Peter , Kosarin, Kristi , Olsh, Adam , Bergeron, Julie , Ellis, Nathan A , Klein, Robert J , Clark, Andrew G , Norton, Larry , Dean, Michael , Boyd, Jeff and Offit, Kenneth
Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
We performed a three-phase genome-wide association study (GWAS) using cases and controls from a genetically isolated population, Ashkenazi Jews (AJ), to identify loci associated with breast cancer risk. In the first phase, we compared allele frequencies of 150,080 SNPs in 249 high-risk, BRCA1/2 mutation-negative AJ familial cases and 299 cancer-fre...
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Full title
Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33
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TN_cdi_proquest_miscellaneous_70423258
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70423258
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0800441105