Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation
Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
This paper examines the link between coagulation and systematic inflammation, and shows that coagulation proteases signal to dendritic cells by activating PAR1, resulting in activation of the shingolipid signalling component and dissemination of inflammation from the lymph nodes to the lungs.
Defining critical points of modulation across heterog...
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Full title
Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation
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TN_cdi_proquest_miscellaneous_70466938
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70466938
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ISSN
0028-0836
E-ISSN
1476-4687,1476-4679
DOI
10.1038/nature06663
