The 2.0 Å structure of human ferrochelatase, the terminal enzyme of heme biosynthesis
The 2.0 Å structure of human ferrochelatase, the terminal enzyme of heme biosynthesis
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Human ferrochelatase (E.C. 4.99.1.1) is a homodimeric (86 kDa) mitochondrial membrane-associated enzyme that catalyzes the insertion of ferrous iron into protoporphyrin to form heme. We have determined the 2.0 Å structure from the single wavelength iron anomalous scattering signal. The enzyme contains two NO-sensitive and uniquely coordinated [2Fe-...
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The 2.0 Å structure of human ferrochelatase, the terminal enzyme of heme biosynthesis
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TN_cdi_proquest_miscellaneous_70642026
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70642026
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1072-8368,1545-9993
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1545-9985
DOI
10.1038/84152
