Polyglutamine and CBP: Fatal attraction?
Polyglutamine and CBP: Fatal attraction?
About this item
Full title
Polyglutamine and CBP: Fatal attraction?
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Nature medicine, 2001-05, Vol.7 (5), p.528-530
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The mutant proteins that cause polyglutamine disease bind CREB-binding protein (CBP), a key transcriptional co-activator for neuronal survival factors. This results in a loss of CBP-dependent transcription and may account for the neuronal degeneration associated with these diseases.
Alternative Titles
Full title
Polyglutamine and CBP: Fatal attraction?
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_70819417
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70819417
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/87842
