The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways
The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways
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Basingstoke: Nature Publishing
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English
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Basingstoke: Nature Publishing
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We utilized a cDNA expression library derived from the B6SutA(1) mouse myeloid progenitor cell line to search for novel oncogenes that promote growth transformation of NIH3T3 cells. A 2.2 kb transforming cDNA was recovered that encodes the wild type thrombin-stimulated G protein-coupled receptor PAR-1. In addition to its potent focus forming activi...
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The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways
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TN_cdi_proquest_miscellaneous_70854733
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70854733
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0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1204281
