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IgA production without μ or δ chain expression in developing B cells

IgA production without μ or δ chain expression in developing B cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70961840

IgA production without μ or δ chain expression in developing B cells

About this item

Full title

IgA production without μ or δ chain expression in developing B cells

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2001-07, Vol.2 (7), p.625-631

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Surface, membrane-bound, immunoglobulin M (IgM) or IgD expression early in B cell ontogeny is considered essential for the differentiation of antibody-producing cells in mammals; only in IgM
+
B cells is the heavy chain locus rearranged to express antibodies of other classes. We show here that IgA is selectively expressed in μMT mice, which l...

Alternative Titles

Full title

IgA production without μ or δ chain expression in developing B cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_70961840

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_70961840

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/89775

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