CD4+T Cells Derived from B Cell-Deficient Mice Inhibit the Establishment of Peripheral B Cell Pools
CD4+T Cells Derived from B Cell-Deficient Mice Inhibit the Establishment of Peripheral B Cell Pools
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United States: National Academy of Sciences of the United States of America
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English
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United States: National Academy of Sciences of the United States of America
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We demonstrate that adoptive transfer of peritoneal cavity B cells fails to replenish the peripheral B-1 cells in adult B cell-deficient (μ-/-) mice but does replenish adult RAG-1-/-mice. We show that this lack of self-replenishment in μ-/-mice is mediated by strongly inhibitory, radiation-sensitive CD4+T cells that also function in cotransfer stud...
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CD4+T Cells Derived from B Cell-Deficient Mice Inhibit the Establishment of Peripheral B Cell Pools
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TN_cdi_proquest_miscellaneous_71076502
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71076502
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.97.9.4766