WT1 is a modifier of the Pax2 mutant phenotype: cooperation and interaction between WT1 and Pax2
WT1 is a modifier of the Pax2 mutant phenotype: cooperation and interaction between WT1 and Pax2
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Metanephric kidney development requires an inductive interaction between the ureteric bud and progenitor mesenchyme, where the early expression of two genes,
Wilms’ tumour 1 (WT1)
and
paired box 2 (Pax2)
, establishes critical but unknown developmental pathways. Indeed, transgenic mice with deregulated overexpression of
Pax2
exhib...
Alternative Titles
Full title
WT1 is a modifier of the Pax2 mutant phenotype: cooperation and interaction between WT1 and Pax2
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TN_cdi_proquest_miscellaneous_71333527
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71333527
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1206997
