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Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to...

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71410420

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells

About this item

Full title

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2003-12, Vol.4 (12), p.1191-1198

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

A major unanswered question is what distinguishes the majority of activated CD8 T cells that die after an acute viral infection from the small fraction (5–10%) that survive to become long-lived memory cells. In this study we show that increased expression of the interleukin 7 receptor α-chain (IL-7Rα) identifies the effector CD8 T cells that will d...

Alternative Titles

Full title

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71410420

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71410420

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni1009

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