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Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a stud...

Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a stud...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71475965

Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a study in rhesus monkeys

About this item

Full title

Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a study in rhesus monkeys

Publisher

London: Elsevier Ltd

Journal title

The Lancet (British edition), 2003-12, Vol.362 (9400), p.1953-1958

Language

English

Formats

Publication information

Publisher

London: Elsevier Ltd

More information

Scope and Contents

Contents

Infection with the Ebola virus induces overexpression of the procoagulant tissue factor in primate monocytes and macrophages, suggesting that inhibition of the tissue-factor pathway could ameliorate the effects of Ebola haemorrhagic fever. Here, we tested the notion that blockade of fVIIa/tissue factor is beneficial after infection with Ebola virus...

Alternative Titles

Full title

Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a study in rhesus monkeys

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71475965

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71475965

Other Identifiers

ISSN

0140-6736

E-ISSN

1474-547X

DOI

10.1016/S0140-6736(03)15012-X

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