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Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione leve...

Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione leve...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71477013

Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels

About this item

Full title

Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2003-12, Vol.22 (58), p.9275-9281

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Nrf2 is a basic leucine zipper transcriptional activator that is essential for the coordinate transcriptional induction of various antioxidant drug-metabolizing enzymes. Numerous studies have firmly established Nrf2's importance in protection from oxidative stress and certain chemical insults. Given the protective function of Nrf2, surprisingly few...

Alternative Titles

Full title

Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71477013

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71477013

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1207024

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