Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Toll-like receptors (TLRs), which recognize pathogen-associated molecular patterns, and members of the pro-inflammatory interleukin-1 receptor (IL-1R) family, share homologies in their cytoplasmic domains called Toll/IL-1R/plant R gene homology (TIR) domains
1
,
2
,
3
. Intracellular signalling mechanisms mediated by TIRs are simi...
Alternative Titles
Full title
Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_71613896
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71613896
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature736
