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Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perina...

Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perina...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71671167

Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival

About this item

Full title

Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival

Publisher

United States: Nature Publishing Group

Journal title

Nature medicine, 2002-05, Vol.8 (5), p.514-517

Language

English

Formats

Publication information

Publisher

United States: Nature Publishing Group

More information

Scope and Contents

Contents

The only proven requirement for ascorbic acid (vitamin C) is in preventing scurvy, presumably because it is a cofactor for hydroxylases required for post-translational modifications that stabilize collagen. We have created mice deficient in the mouse ortholog (solute carrier family 23 member 1 or Slc23a1) of a rat ascorbic-acid transporter, Svct2 (...

Alternative Titles

Full title

Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71671167

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71671167

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/0502-514

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