Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P30...
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
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Author / Creator
Lewis, Jada , McGowan, Eileen , Rockwood, Julia , Melrose, Heather , Nacharaju, Parimala , Van Slegtenhorst, Marjon , Gwinn-Hardy, Katrina , Murphy, M. P , Baker, Matt , Yu, Xin , Duff, Karen , Hardy, John , Corral, Anthony , Lin, Wen-Lang , Yen, Shu-Hui , Dickson, Dennis W. , Davies, Peter and Hutton, Mike
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Neurofibrillary tangles (NFT) composed of the microtubule-associated protein tau are prominent in Alzheimer disease (AD), Pick disease, progressive supranuclear palsy (PSP) and corticobasal degeneration
1
(CBD). Mutations in the gene (
Mtapt
) encoding tau protein cause frontotemporal dementia and parkinsonism linked to chromosome 17 (F...
Alternative Titles
Full title
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
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Record Identifier
TN_cdi_proquest_miscellaneous_71739367
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71739367
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/78078
