Initiation of neuronal damage by complex I deficiency and oxidative stress in Parkinson's disease
Initiation of neuronal damage by complex I deficiency and oxidative stress in Parkinson's disease
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United States: Springer Nature B.V
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Language
English
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Publisher
United States: Springer Nature B.V
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Contents
Oxidative stress and partial deficiencies of mitochondrial complex I appear to be key factors in the pathogenesis of Parkinson's disease. They are interconnected; complex I inhibition results in an enhanced production of reactive oxygen species (ROS), which in turn will inhibit complex I. Partial inhibition of complex I in nerve terminals is suffic...
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Full title
Initiation of neuronal damage by complex I deficiency and oxidative stress in Parkinson's disease
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TN_cdi_proquest_miscellaneous_71749585
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71749585
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ISSN
0364-3190
E-ISSN
1573-6903
DOI
10.1023/B:NERE.0000014827.94562.4b
