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A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progressi...

A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progressi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71876018

A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression

About this item

Full title

A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression

Publisher

England

Journal title

The EMBO journal, 2002-07, Vol.21 (13), p.3390-3401

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

The cyclin-dependent kinase inhibitor, p27(Kip1), which regulates cell cycle progression, is controlled by its subcellular localization and subsequent degradation. p27(Kip1) is phosphorylated on serine 10 (S10) and threonine 187 (T187). Although the role of T187 and its phosphorylation by Cdks is well-known, the kinase that phosphorylates S10 and i...

Alternative Titles

Full title

A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_71876018

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_71876018

Other Identifiers

ISSN

0261-4189

DOI

10.1093/emboj/cdf343

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