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ArticlesPeer ReviewedFull Text
Human blood vessel organoids as a model of diabetic vasculopathy
Author / Creator:Wimmer, Reiner A. ; Leopoldi, Alexandra ; Aichinger, Martin ; Wick, Nikolaus ; Hantusch, Brigitte ; Novatchkova, Maria ; Taubenschmid, Jasmin ; Hämmerle, Monika ; Esk, Christopher ; Bagley, Joshua A. ; Lindenhofer, Dominik ; Chen, Guibin ; Boehm, Manfred ; Agu, Chukwuma A. ; Yang, Fengtang ; Fu, Beiyuan ; Zuber, Johannes ; Knoblich, Juergen A. ; Kerjaschki, Dontscho ; Penninger, Josef M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-01, Vol.565 (7740), p.505-510
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Bone marrow–derived immune cells regulate vascular disease through a p27Kip1-dependent mechanism
Author / Creator:Boehm, Manfred ; Olive, Michelle ; True, Andrea L. ; Crook, Martin F. ; San, Hong ; Qu, Xuan ; Nabel, Elizabeth G.
Journal title:The Journal of clinical investigation, 2004-08, Vol.114 (3), p.419-426
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ArticlesPeer ReviewedFull Text
Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability
Author / Creator:Evrard, Solene M. ; Lecce, Laura ; Michelis, Katherine C. ; Nomura-Kitabayashi, Aya ; Pandey, Gaurav ; Purushothaman, K-Raman ; d’Escamard, Valentina ; Li, Jennifer R. ; Hadri, Lahouaria ; Fujitani, Kenji ; Moreno, Pedro R. ; Benard, Ludovic ; Rimmele, Pauline ; Cohain, Ariella ; Mecham, Brigham ; Randolph, Gwendalyn J. ; Nabel, Elizabeth G. ; Hajjar, Roger ; Fuster, Valentin ; Boehm, Manfred ; Kovacic, Jason C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-06, Vol.7 (1), p.11853-11853, Article 11853
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ArticlesPeer ReviewedFull Text
Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease
Author / Creator:Zhou, Qing ; Wang, Hongying ; Schwartz, Daniella M ; Stoffels, Monique ; Park, Yong Hwan ; Zhang, Yuan ; Yang, Dan ; Demirkaya, Erkan ; Takeuchi, Masaki ; Tsai, Wanxia Li ; Lyons, Jonathan J ; Yu, Xiaomin ; Ouyang, Claudia ; Chen, Celeste ; Chin, David T ; Zaal, Kristien ; Chandrasekharappa, Settara C ; P Hanson, Eric ; Yu, Zhen ; Mullikin, James C ; Hasni, Sarfaraz A ; Wertz, Ingrid E ; Ombrello, Amanda K ; Stone, Deborah L ; Hoffmann, Patrycja ; Jones, Anne ; Barham, Beverly K ; Leavis, Helen L ; van Royen-Kerkof, Annet ; Sibley, Cailin ; Batu, Ezgi D ; Gül, Ahmet ; Siegel, Richard M ; Boehm, Manfred ; Milner, Joshua D ; Ozen, Seza ; Gadina, Massimo ; Chae, JaeJin ; Laxer, Ronald M ; Kastner, Daniel L ; Aksentijevich, Ivona
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2016-01, Vol.48 (1), p.67-73
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ArticlesPeer ReviewedFull Text
Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease
Author / Creator:Zhou, Qing ; Yu, Xiaomin ; Demirkaya, Erkan ; Deuitch, Natalie ; Stone, Deborah ; Tsai, Wanxia Li ; Kuehn, Hye Sun ; Wang, Hongying ; Yang, Dan ; Park, Yong Hwan ; Ombrello, Amanda K. ; Blake, Mary ; Romeo, Tina ; Remmers, Elaine F. ; Chae, Jae Jin ; Mullikin, James C. ; Güzel, Ferhat ; Milner, Joshua D. ; Boehm, Manfred ; Rosenzweig, Sergio D. ; Gadina, Massimo ; Welch, Steven B. ; Özen, Seza ; Topaloglu, Rezan ; Abinun, Mario ; Kastner, Daniel L. ; Aksentijevich, Ivona
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (36), p.10127-10132
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ArticlesPeer ReviewedFull Text
p53 Regulates Mitochondrial Respiration
Author / Creator:Matoba, Satoaki ; Kang, Ju-Gyeong ; Patino, Willmar D ; Wragg, Andrew ; Boehm, Manfred ; Gavrilova, Oksana ; Hurley, Paula J ; Bunz, Fred ; Hwang, Paul M
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2006-06, Vol.312 (5780), p.1650-1653
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ArticlesPeer ReviewedFull Text
In vivo transplantation of mammalian vascular organoids onto the chick chorioallantoic membrane reveals the formation of a hierarchical vascular network
Author / Creator:Kowalski, William J. ; Vatti, Shravani ; Sakamoto, Tyler ; Li, Wenling ; Odutola, Sarah Rose ; Liu, Chengyu ; Chen, Guibin ; Boehm, Manfred ; Mukouyama, Yoh-suke
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-02, Vol.15 (1), p.7150-13
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Newsletter articlesFull Text
WIPO PUBLISHES PATENT OF MARC PEUKER, HELMUT PAUSER, JENS GRAMANN, ANDREAS J. BOEHM, MANFRED HARRE AND 3M INNOVATIVE PROPERTIES FOR "CARTRIDGE FOR DISPENSING A DENTAL SUBSTANCE AND METHOD OF ASSEMBLIN...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2013
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ArticlesPeer ReviewedFull Text
Efficient differentiation of cardiomyocytes and generation of calcium-sensor reporter lines from nonhuman primate iPSCs
Author / Creator:Lin, Yongshun ; Liu, Huimin ; Klein, Michael ; Ostrominski, John ; Hong, So Gun ; Yada, Ravi Chandra ; Chen, Guibin ; Navarengom, Keron ; Schwartzbeck, Robin ; San, Hong ; Yu, Zu-Xi ; Liu, Chengyu ; Linask, Kaari ; Beers, Jeanette ; Qiu, Lugui ; Dunbar, Cynthia E. ; Boehm, Manfred ; Zou, Jizhong
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-04, Vol.8 (1), p.5907-16, Article 5907
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ArticlesPeer ReviewedFull Text
Histone H2AX is integral to hypoxia-driven neovascularization
Author / Creator:Economopoulou, Matina ; Langer, Harald F ; Celeste, Arkady ; Orlova, Valeria V ; Choi, Eun Young ; Ma, Mingchao ; Vassilopoulos, Athanassios ; Callen, Elsa ; Deng, Chuxia ; Bassing, Craig H ; Boehm, Manfred ; Nussenzweig, Andre ; Chavakis, Triantafyllos
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2009-05, Vol.15 (5), p.553-558
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ArticlesPeer ReviewedFull Text
CRISPR/Cas9‐mediated introduction of the sodium/iodide symporter gene enables noninvasive in vivo tracking of induced pluripotent stem cell‐derived cardiomyocytes
Author / Creator:Ostrominski, John W. ; Yada, Ravi Chandra ; Sato, Noriko ; Klein, Michael ; Blinova, Ksenia ; Patel, Dakshesh ; Valadez, Racquel ; Palisoc, Maryknoll ; Pittaluga, Stefania ; Peng, Kah‐Whye ; San, Hong ; Lin, Yongshun ; Basuli, Falguni ; Zhang, Xiang ; Swenson, Rolf E. ; Haigney, Mark ; Choyke, Peter L. ; Zou, Jizhong ; Boehm, Manfred ; Hong, So Gun ; Dunbar, Cynthia E.
Publisher:Hoboken, USA: John Wiley & Sons, Inc
Journal title:Stem cells translational medicine, 2020-10, Vol.9 (10), p.1203-1217
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ArticlesPeer ReviewedFull Text
Correction: Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability
Author / Creator:Evrard, Solene M. ; Lecce, Laura ; Michelis, Katherine C. ; Nomura-Kitabayashi, Aya ; Pandey, Gaurav ; Purushothaman, K-Raman ; d’Escamard, Valentina ; Li, Jennifer R. ; Hadri, Lahouaria ; Fujitani, Kenji ; Moreno, Pedro R. ; Benard, Ludovic ; Rimmele, Pauline ; Cohain, Ariella ; Mecham, Brigham ; Randolph, Gwendalyn J. ; Nabel, Elizabeth G. ; Hajjar, Roger ; Fuster, Valentin ; Boehm, Manfred ; Kovacic, Jason C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-02, Vol.8 (1), p.1-1, Article 14710
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ArticlesPeer ReviewedFull Text
STAT3 modulates reprogramming efficiency of human somatic cells; insights from autosomal dominant Hyper IgE syndrome caused by STAT3 mutations
Author / Creator:Yu, Zhen ; Dmitrieva, Natalia I ; Walts, Avram D ; Jin, Hui ; Liu, Yangtengyu ; Ping, Xianfeng ; Ferrante, Elisa A ; Qiu, Lugui ; Holland, Steven M ; Freeman, Alexandra F ; Chen, Guibin ; Boehm, Manfred
Publisher:England: The Company of Biologists Ltd
Journal title:Biology open, 2020-09, Vol.9 (9)
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ArticlesPeer ReviewedFull Text
The NIH Undiagnosed Diseases Program: bonding scientists and clinicians
Author / Creator:Gahl, William A ; Boerkoel, Cornelius F ; Boehm, Manfred
Publisher:England: The Company of Biologists Ltd
Journal title:Disease models & mechanisms, 2012-01, Vol.5 (1), p.3-5
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ArticlesPeer ReviewedFull Text
p21Cip1 modulates arterial wound repair through the stromal cell-derived factor-1/CXCR4 axis in mice
Author / Creator:Olive, Michelle ; Mellad, Jason A ; Beltran, Leilani E ; Ma, Mingchao ; Cimato, Thomas ; Noguchi, Audrey C ; San, Hong ; Childs, Richard ; Kovacic, Jason C ; Boehm, Manfred
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2008-05, Vol.118 (6), p.2050-2061
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ArticlesPeer ReviewedFull Text
Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease
Author / Creator:Lalaoui, Najoua ; Boyden, Steven E. ; Oda, Hirotsugu ; Wood, Geryl M. ; Stone, Deborah L. ; Chau, Diep ; Liu, Lin ; Stoffels, Monique ; Kratina, Tobias ; Lawlor, Kate E. ; Zaal, Kristien J. M. ; Hoffmann, Patrycja M. ; Etemadi, Nima ; Shield-Artin, Kristy ; Biben, Christine ; Tsai, Wanxia Li ; Blake, Mary D. ; Kuehn, Hye Sun ; Yang, Dan ; Anderton, Holly ; Silke, Natasha ; Wachsmuth, Laurens ; Zheng, Lixin ; Moura, Natalia Sampaio ; Beck, David B. ; Gutierrez-Cruz, Gustavo ; Ombrello, Amanda K. ; Pinto-Patarroyo, Gineth P. ; Kueh, Andrew J. ; Herold, Marco J. ; Hall, Cathrine ; Wang, Hongying ; Chae, Jae Jin ; Dmitrieva, Natalia I. ; McKenzie, Mark ; Light, Amanda ; Barham, Beverly K. ; Jones, Anne ; Romeo, Tina M. ; Zhou, Qing ; Aksentijevich, Ivona ; Mullikin, James C. ; Gross, Andrew J. ; Shum, Anthony K. ; Hawkins, Edwin D. ; Masters, Seth L. ; Lenardo, Michael J. ; Boehm, Manfred ; Rosenzweig, Sergio D. ; Pasparakis, Manolis ; Voss, Anne K. ; Gadina, Massimo ; Kastner, Daniel L. ; Silke, John
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-01, Vol.577 (7788), p.103-108
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ArticlesPeer ReviewedFull Text
Development of vascular disease models to explore disease causation and pathomechanisms of rare vascular diseases
Author / Creator:Harper, Rebecca L. ; Ferrante, Elisa A. ; Boehm, Manfred
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Seminars in immunopathology, 2022-05, Vol.44 (3), p.259-268
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Bioprinted 3D outer retina barrier uncovers RPE-dependent choroidal phenotype in advanced macular degeneration
Author / Creator:Song, Min Jae ; Quinn, Russ ; Nguyen, Eric ; Hampton, Christopher ; Sharma, Ruchi ; Park, Tea Soon ; Koster, Céline ; Voss, Ty ; Tristan, Carlos ; Weber, Claire ; Singh, Anju ; Dejene, Roba ; Bose, Devika ; Chen, Yu-Chi ; Derr, Paige ; Derr, Kristy ; Michael, Sam ; Barone, Francesca ; Chen, Guibin ; Boehm, Manfred ; Maminishkis, Arvydas ; Singec, Ilyas ; Ferrer, Marc ; Bharti, Kapil
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2023-01, Vol.20 (1), p.149-161
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ArticlesPeer ReviewedFull Text
Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype
Author / Creator:Lecce, Laura ; Xu, Yang ; V'Gangula, Bhargavi ; Chandel, Nirupama ; Pothula, Venu ; Caudrillier, Axelle ; Santini, Maria Paola ; d'Escamard, Valentina ; Ceholski, Delaine K ; Gorski, Przemek A ; Ma, Lijiang ; Koplev, Simon ; Bjørklund, Martin Mæng ; Björkegren, Johan Lm ; Boehm, Manfred ; Bentzon, Jacob Fog ; Fuster, Valentin ; Kim, Ha Won ; Weintraub, Neal L ; Baker, Andrew H ; Bernstein, Emily ; Kovacic, Jason C
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-08, Vol.131 (15)
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ArticlesPeer ReviewedFull Text
Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2
Author / Creator:Zhou, Qing ; Yang, Dan ; Ombrello, Amanda K ; Zavialov, Andrey V ; Toro, Camilo ; Zavialov, Anton V ; Stone, Deborah L ; Chae, Jae Jin ; Rosenzweig, Sergio D ; Bishop, Kevin ; Barron, Karyl S ; Kuehn, Hye Sun ; Hoffmann, Patrycja ; Negro, Alejandra ; Tsai, Wanxia L ; Cowen, Edward W ; Pei, Wuhong ; Milner, Joshua D ; Silvin, Christopher ; Heller, Theo ; Chin, David T ; Patronas, Nicholas J ; Barber, John S ; Lee, Chyi-Chia R ; Wood, Geryl M ; Ling, Alexander ; Kelly, Susan J ; Kleiner, David E ; Mullikin, James C ; Ganson, Nancy J ; Kong, Heidi H ; Hambleton, Sophie ; Candotti, Fabio ; Quezado, Martha M ; Calvo, Katherine R ; Alao, Hawwa ; Barham, Beverly K ; Jones, Anne ; Meschia, James F ; Worrall, Bradford B ; Kasner, Scott E ; Rich, Stephen S ; Goldbach-Mansky, Raphaela ; Abinun, Mario ; Chalom, Elizabeth ; Gotte, Alisa C ; Punaro, Marilynn ; Pascual, Virginia ; Verbsky, James W ; Torgerson, Troy R ; Singer, Nora G ; Gershon, Timothy R ; Ozen, Seza ; Karadag, Omer ; Fleisher, Thomas A ; Remmers, Elaine F ; Burgess, Shawn M ; Moir, Susan L ; Gadina, Massimo ; Sood, Raman ; Hershfield, Michael S ; Boehm, Manfred ; Kastner, Daniel L ; Aksentijevich, Ivona
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-03, Vol.370 (10), p.911-920
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Human blood vessel organoids as a model of diabetic vasculopathy

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Bone marrow–derived immune cells regulate vascular disease through a p27Kip1-dependent mechanism

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Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability

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Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease

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Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease

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p53 Regulates Mitochondrial Respiration

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In vivo transplantation of mammalian vascular organoids onto the chick chorioallantoic membrane reveals the formation of a hierarchical vascular network

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WIPO PUBLISHES PATENT OF MARC PEUKER, HELMUT PAUSER, JENS GRAMANN, ANDREAS J. BOEHM, MANFRED HARRE AND 3M INNOVATIVE PROPERTIES FOR "CARTRIDGE FOR DISPENSING A DENTAL SUBSTANCE AND METHOD OF ASSEMBLIN...

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Efficient differentiation of cardiomyocytes and generation of calcium-sensor reporter lines from nonhuman primate iPSCs

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Histone H2AX is integral to hypoxia-driven neovascularization

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CRISPR/Cas9‐mediated introduction of the sodium/iodide symporter gene enables noninvasive in vivo tracking of induced pluripotent stem cell‐derived cardiomyocytes

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Correction: Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability

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STAT3 modulates reprogramming efficiency of human somatic cells; insights from autosomal dominant Hyper IgE syndrome caused by STAT3 mutations

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The NIH Undiagnosed Diseases Program: bonding scientists and clinicians

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p21Cip1 modulates arterial wound repair through the stromal cell-derived factor-1/CXCR4 axis in mice

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Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease

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Development of vascular disease models to explore disease causation and pathomechanisms of rare vascular diseases

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Bioprinted 3D outer retina barrier uncovers RPE-dependent choroidal phenotype in advanced macular degeneration

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Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype

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Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2

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