Loss of SM-B myosin affects muscle shortening velocity and maximal force development
Loss of SM-B myosin affects muscle shortening velocity and maximal force development
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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We used an exon-specific gene-targeting strategy to generate a mouse model deficient only in the SM-B myosin isoform. Here we show that deletion of exon-5B (specific for SM-B) in the gene for the heavy chain of smooth muscle myosin results in a complete loss of SM-B myosin and switching of splicing to the SM-A isoform, without affecting SM1 and SM2...
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Full title
Loss of SM-B myosin affects muscle shortening velocity and maximal force development
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TN_cdi_proquest_miscellaneous_72289384
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72289384
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ISSN
1465-7392,1476-4679
E-ISSN
1476-4679
DOI
10.1038/ncb1101-1025
