NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway
NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Using a mouse model in which tumors show a growth-regression-recurrence pattern, we investigated the mechanisms for down-regulation of cytotoxic T lymphocyte–mediated tumor immuno-surveillance. We found that interleukin 4 receptor (IL-4R) knockout and downstream signal transducer and activator of transcription 6 (STAT6) knockout, but not IL-4 knock...
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NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway
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TN_cdi_proquest_miscellaneous_72595196
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72595196
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/82771