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NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway

NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72595196

NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway

About this item

Full title

NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2000-12, Vol.1 (6), p.515-520

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Using a mouse model in which tumors show a growth-regression-recurrence pattern, we investigated the mechanisms for down-regulation of cytotoxic T lymphocyte–mediated tumor immuno-surveillance. We found that interleukin 4 receptor (IL-4R) knockout and downstream signal transducer and activator of transcription 6 (STAT6) knockout, but not IL-4 knock...

Alternative Titles

Full title

NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_72595196

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_72595196

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/82771

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