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Neuronal overexpression of COX-2 results in dominant production of PGE2 and altered fever response

Neuronal overexpression of COX-2 results in dominant production of PGE2 and altered fever response

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73140297

Neuronal overexpression of COX-2 results in dominant production of PGE2 and altered fever response

About this item

Full title

Neuronal overexpression of COX-2 results in dominant production of PGE2 and altered fever response

Publisher

United States: Springer Nature B.V

Journal title

Neuromolecular medicine, 2003, Vol.3 (1), p.15-28

Language

English

Formats

Publication information

Publisher

United States: Springer Nature B.V

More information

Scope and Contents

Contents

Cyclooxygenases catalyze the first committed step in the formation of prostaglandins and thromboxanes from arachidonic acid. Cyclooxygenase-2 (COX-2), the inducible isoform of cyclooxygenase, is expressed in brain selectively in neurons of hippocampus, cerebral cortex, amygdala, and hypothalamus. Prostaglandins function in many processes in the CNS...

Alternative Titles

Full title

Neuronal overexpression of COX-2 results in dominant production of PGE2 and altered fever response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_73140297

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73140297

Other Identifiers

ISSN

1535-1084

E-ISSN

1535-1084,1559-1174

DOI

10.1385/NMM:3:1:15

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