ZAP-70 Expression as a Surrogate for Immunoglobulin-Variable-Region Mutations in Chronic Lymphocytic...
ZAP-70 Expression as a Surrogate for Immunoglobulin-Variable-Region Mutations in Chronic Lymphocytic Leukemia
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Publisher
Boston, MA: Massachusetts Medical Society
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Language
English
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Publisher
Boston, MA: Massachusetts Medical Society
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Scope and Contents
Contents
Mutations of immunoglobulin genes in chronic-lymphocytic-leukemia (CLL) cells augur a good outcome, whereas the absence of mutations indicates a poor prognosis. The presence of ZAP-70 on CLL cells correlated with unmutated immunoglobulin genes and a poor prognosis, whereas its absence indicated the presence of mutated genes and a good outcome.
T...
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Full title
ZAP-70 Expression as a Surrogate for Immunoglobulin-Variable-Region Mutations in Chronic Lymphocytic Leukemia
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TN_cdi_proquest_miscellaneous_73235100
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73235100
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa023143
