Narcolepsy is strongly associated with the T-cell receptor alpha locus
Narcolepsy is strongly associated with the T-cell receptor alpha locus
About this item
Full title
Author / Creator
Hallmayer, Joachim , Faraco, Juliette , Lin, Ling , Hesselson, Stephanie , Winkelmann, Juliane , Kawashima, Minae , Mayer, Geert , Plazzi, Giuseppe , Nevsimalova, Sona , Bourgin, Patrice , Hong, Seung-Chul , Honda, Yutaka , Honda, Makoto , Högl, Birgit , Longstreth, William T , Montplaisir, Jacques , Kemlink, David , Einen, Mali , Chen, Justin , Musone, Stacy L , Akana, Matthew , Miyagawa, Taku , Duan, Jubao , Desautels, Alex , Erhardt, Christine , Hesla, Per Egil , Poli, Francesca , Frauscher, Birgit , Jeong, Jong-Hyun , Lee, Sung-Pil , Ton, Thanh G N , Kvale, Mark , Kolesar, Libor , Dobrovolná, Marie , Nepom, Gerald T , Salomon, Dan , Wichmann, H-Erich , Rouleau, Guy A , Gieger, Christian , Levinson, Douglas F , Gejman, Pablo V , Meitinger, Thomas , Young, Terry , Peppard, Paul , Tokunaga, Katsushi , Kwok, Pui-Yan , Risch, Neil and Mignot, Emmanuel
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Emmanuel Mignot and colleagues report that variants in the T-cell receptor alpha (
TRA@
) locus are strongly associated with narcolepsy. This is the first documented involvement of the TCR locus in human disease and will shed light on how HLA-TCR interactions contribute to organ-specific autoimmune targeting.
Narcolepsy with cataplexy, cha...
Alternative Titles
Full title
Narcolepsy is strongly associated with the T-cell receptor alpha locus
Authors, Artists and Contributors
Author / Creator
Faraco, Juliette
Lin, Ling
Hesselson, Stephanie
Winkelmann, Juliane
Kawashima, Minae
Mayer, Geert
Plazzi, Giuseppe
Nevsimalova, Sona
Bourgin, Patrice
Hong, Seung-Chul
Honda, Yutaka
Honda, Makoto
Högl, Birgit
Longstreth, William T
Montplaisir, Jacques
Kemlink, David
Einen, Mali
Chen, Justin
Musone, Stacy L
Akana, Matthew
Miyagawa, Taku
Duan, Jubao
Desautels, Alex
Erhardt, Christine
Hesla, Per Egil
Poli, Francesca
Frauscher, Birgit
Jeong, Jong-Hyun
Lee, Sung-Pil
Ton, Thanh G N
Kvale, Mark
Kolesar, Libor
Dobrovolná, Marie
Nepom, Gerald T
Salomon, Dan
Wichmann, H-Erich
Rouleau, Guy A
Gieger, Christian
Levinson, Douglas F
Gejman, Pablo V
Meitinger, Thomas
Young, Terry
Peppard, Paul
Tokunaga, Katsushi
Kwok, Pui-Yan
Risch, Neil
Mignot, Emmanuel
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_733101577
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733101577
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.372
