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Daunomycin accumulation and induction of programmed cell death in rat hair follicles

Daunomycin accumulation and induction of programmed cell death in rat hair follicles

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733945299

Daunomycin accumulation and induction of programmed cell death in rat hair follicles

About this item

Full title

Daunomycin accumulation and induction of programmed cell death in rat hair follicles

Publisher

Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag

Journal title

Cell and tissue research, 2009-09, Vol.337 (3), p.429-438

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag

More information

Scope and Contents

Contents

The anthracycline antibiotic daunomycin (DM) is useful for the treatment of leukemia but has side-effects such as alopecia. Using immunocytochemistry, we show that, after a single i.v. injection, DM accumulates in the nuclei of matrix cells and in the outer root sheath of hair follicles. DM-positive matrix cells are detectable up to 48 h after inje...

Alternative Titles

Full title

Daunomycin accumulation and induction of programmed cell death in rat hair follicles

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_733945299

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733945299

Other Identifiers

ISSN

0302-766X

E-ISSN

1432-0878

DOI

10.1007/s00441-009-0840-8

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