Daunomycin accumulation and induction of programmed cell death in rat hair follicles
Daunomycin accumulation and induction of programmed cell death in rat hair follicles
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Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Language
English
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Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Contents
The anthracycline antibiotic daunomycin (DM) is useful for the treatment of leukemia but has side-effects such as alopecia. Using immunocytochemistry, we show that, after a single i.v. injection, DM accumulates in the nuclei of matrix cells and in the outer root sheath of hair follicles. DM-positive matrix cells are detectable up to 48 h after inje...
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Full title
Daunomycin accumulation and induction of programmed cell death in rat hair follicles
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TN_cdi_proquest_miscellaneous_733945299
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_733945299
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ISSN
0302-766X
E-ISSN
1432-0878
DOI
10.1007/s00441-009-0840-8