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Induced Chromosomal Proximity and Gene Fusions in Prostate Cancer

Induced Chromosomal Proximity and Gene Fusions in Prostate Cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734175555

Induced Chromosomal Proximity and Gene Fusions in Prostate Cancer

About this item

Full title

Induced Chromosomal Proximity and Gene Fusions in Prostate Cancer

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2009-11, Vol.326 (5957), p.1230-1230

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Gene fusions play a critical role in cancer progression. The mechanisms underlying their genesis and cell type specificity are not well understood. About 50% of human prostate cancers display a gene fusion involving the 5' untranslated region of TMPRSS2, an androgen-regulated gene, and the protein-coding sequences of ERG, which encodes an erythrobl...

Alternative Titles

Full title

Induced Chromosomal Proximity and Gene Fusions in Prostate Cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_734175555

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_734175555

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1178124

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