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Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers
Author / Creator:Chen, Fengju ; Chandrashekar, Darshan S. ; Varambally, Sooryanarayana ; Creighton, Chad J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-12, Vol.10 (1), p.5679-15, Article 5679
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Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways
Author / Creator:Zhang, Yiqun ; Chen, Fengju ; Chandrashekar, Darshan S. ; Varambally, Sooryanarayana ; Creighton, Chad J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-05, Vol.13 (1), p.2669-19, Article 2669
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Comparative transcriptome analyses reveal genes associated with SARS-CoV-2 infection of human lung epithelial cells
Author / Creator:Chandrashekar, Darshan S. ; Athar, Mohammad ; Manne, Upender ; Varambally, Sooryanarayana
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-08, Vol.11 (1), p.16212-16212, Article 16212
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Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
Author / Creator:Beltran, Himisha ; Prandi, Davide ; Mosquera, Juan Miguel ; Benelli, Matteo ; Puca, Loredana ; Cyrta, Joanna ; Marotz, Clarisse ; Giannopoulou, Eugenia ; Chakravarthi, Balabhadrapatruni V S K ; Varambally, Sooryanarayana ; Tomlins, Scott A ; Nanus, David M ; Tagawa, Scott T ; Van Allen, Eliezer M ; Elemento, Olivier ; Sboner, Andrea ; Garraway, Levi A ; Rubin, Mark A ; Demichelis, Francesca
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2016-03, Vol.22 (3), p.298-305
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Global impact of somatic structural variation on the cancer proteome
Author / Creator:Chen, Fengju ; Zhang, Yiqun ; Chandrashekar, Darshan S. ; Varambally, Sooryanarayana ; Creighton, Chad J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-09, Vol.14 (1), p.5637-19, Article 5637
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Induced Chromosomal Proximity and Gene Fusions in Prostate Cancer
Author / Creator:Mani, Ram-Shankar ; Tomlins, Scott A ; Callahan, Kaitlin ; Ghosh, Aparna ; Nyati, Mukesh K ; Varambally, Sooryanarayana ; Palanisamy, Nallasivam ; Chinnaiyan, Arul M
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2009-11, Vol.326 (5957), p.1230-1230
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Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers
Author / Creator:Monsivais, Diana ; Vasquez, Yasmin M. ; Chen, Fengju ; Zhang, Yiqun ; Chandrashekar, Darshan S. ; Faver, John C. ; Masand, Ramya P. ; Scheurer, Michael E. ; Varambally, Sooryanarayana ; Matzuk, Martin M. ; Creighton, Chad J.
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2021-03, Vol.40 (11), p.2081-2095
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Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer
Author / Creator:Varambally, Sooryanarayana ; Cao, Qi ; Mani, Ram-Shankar ; Shankar, Sunita ; Wang, Xiaosong ; Ateeq, Bushra ; Laxman, Bharathi ; Cao, Xuhong ; Jing, Xiaojun ; Ramnarayanan, Kalpana ; Brenner, J. Chad ; Yu, Jindan ; Kim, Jung H ; Han, Bo ; Tan, Patrick ; Kumar-Sinha, Chandan ; Lonigro, Robert J ; Palanisamy, Nallasivam ; Maher, Christopher A ; Chinnaiyan, Arul M
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2008-12, Vol.322 (5908), p.1695-1699
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Author Correction: Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways
Author / Creator:Zhang, Yiqun ; Chen, Fengju ; Chandrashekar, Darshan S. ; Varambally, Sooryanarayana ; Creighton, Chad J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-08, Vol.13 (1), p.4688-4688, Article 4688
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The effect of paclitaxel- and fisetin-loaded PBM nanoparticles on apoptosis and reversal of drug resistance gene ABCG2 in ovarian cancer
Author / Creator:McFadden, Melayshia ; Singh, Santosh Kumar ; Kinnel, Briana ; Varambally, Sooryanarayana ; Singh, Rajesh
Publisher:England: BioMed Central Ltd
Journal title:Journal of ovarian research, 2023-11, Vol.16 (1), p.220-220, Article 220
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DCZ0415, a small‐molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β‐catenin pathway in colorectal cancer
Author / Creator:Agarwal, Sumit ; Afaq, Farrukh ; Bajpai, Prachi ; Kim, Hyung‐Gyoon ; Elkholy, Amr ; Behring, Michael ; Chandrashekar, Darshan Shimoga ; Diffalha, Sameer Al ; Khushman, Moh’d ; Sugandha, Shajan P. ; Varambally, Sooryanarayana ; Manne, Upender
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2022-04, Vol.16 (8), p.1728-1745
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Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
Author / Creator:Tomlins, Scott A. ; Laxman, Bharathi ; Dhanasekaran, Saravana M. ; Helgeson, Beth E. ; Cao, Xuhong ; Morris, David S. ; Menon, Anjana ; Jing, Xiaojun ; Cao, Qi ; Han, Bo ; Yu, Jindan ; Wang, Lei ; Montie, James E. ; Rubin, Mark A. ; Pienta, Kenneth J. ; Roulston, Diane ; Shah, Rajal B. ; Varambally, Sooryanarayana ; Mehra, Rohit ; Chinnaiyan, Arul M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature, 2007-08, Vol.448 (7153), p.595-599
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C/EBPβ increases tumor aggressiveness by enhancing KIFC1 expression in androgen receptor negative triple negative breast cancer
Author / Creator:Joshi, Shriya ; Garlapati, Chakravarthy ; Nguyen, Thi ; Sharma, Shaligram ; Chandrashekar, Darshan Shimoga ; Bhattarai, Shristi ; Varambally, Sooryanarayana ; Krishnamurti, Uma ; Li, Xiaoxian ; Aneja, Ritu
Publisher:England: BioMed Central
Journal title:Cell communication and signaling, 2025-05, Vol.23 (1), p.255-16
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Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression
Author / Creator:Chandrashekar, Darshan S. ; Chakravarthi, Balabhadrapatruni V. S. K. ; Robinson, Alyncia D. ; Anderson, Joshua C. ; Agarwal, Sumit ; Balasubramanya, Sai Akshaya Hodigere ; Eich, Marie-Lisa ; Bajpai, Akhilesh Kumar ; Davuluri, Sravanthi ; Guru, Maya S. ; Guru, Arjun S. ; Naik, Gurudatta ; Della Manna, Deborah L. ; Acharya, Kshitish K. ; Carskadon, Shannon ; Manne, Upender ; Crossman, David K. ; Ferguson, James E. ; Grizzle, William E. ; Palanisamy, Nallasivam ; Willey, Christopher D. ; Crowley, Michael R. ; Netto, George J. ; Yang, Eddy S. ; Varambally, Sooryanarayana ; Sonpavde, Guru
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-05, Vol.39 (20), p.4077-4091
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Combination of dual JAK/HDAC inhibitor with regorafenib synergistically reduces tumor growth, metastasis, and regorafenib-induced toxicity in colorectal cancer
Author / Creator:Bajpai, Prachi ; Agarwal, Sumit ; Afaq, Farrukh ; Al Diffalha, Sameer ; Chandrashekar, Darshan S. ; Kim, Hyung-Gyoon ; Shelton, Abigail ; Miller, C. Ryan ; Singh, Santosh K. ; Singh, Rajesh ; Varambally, Sooryanarayana ; Nagaraju, Ganji Purnachandra ; Manne, Ashish ; Paluri, Ravi ; Khushman, Moh’d ; Manne, Upender
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2024-07, Vol.43 (1), p.192-18, Article 192
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Meta-analysis of the robustness of COVID-19 diagnostic kit performance during the early pandemic
Author / Creator:Shanmugam, Chandrakumar ; Behring, Michael ; Luthra, Vishwas ; Leal, Sixto M ; Varambally, Sooryanarayana ; Netto, George J ; Manne, Upender
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ open, 2022-04, Vol.12 (4), p.e053912-e053912
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Fermentable fiber-induced hepatocellular carcinoma in mice recapitulates gene signatures found in human liver cancer
Author / Creator:Chandrashekar, Darshan Shimoga ; Golonka, Rachel M. ; Yeoh, Beng San ; Gonzalez, David J. ; Heikenwälder, Mathias ; Gerwirtz, Andrew T. ; Varambally, Sooryanarayana ; Vijay-Kumar, Matam
Publisher:San Francisco: Public Library of Science
Journal title:PloS one, 2020-06, Vol.15 (6), p.e0234726-e0234726
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Probabilistic model of the human protein-protein interaction network
Author / Creator:Rhodes, Daniel R ; Tomlins, Scott A ; Varambally, Sooryanarayana ; Mahavisno, Vasudeva ; Barrette, Terrence ; Kalyana-Sundaram, Shanker ; Ghosh, Debashis ; Pandey, Akhilesh ; Chinnaiyan, Arul M
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2005-08, Vol.23 (8), p.951-959
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The combined survival effect of codon 72 polymorphisms and p53 somatic mutations in breast cancer depends on race and molecular subtype
Author / Creator:Hebert-Magee, Shantel ; Yu, Han ; Behring, Michael ; Jadhav, Trafina ; Shanmugam, Chandrakumar ; Frost, Andra ; Eltoum, Isam-Eldin ; Varambally, Sooryanarayana ; Manne, Upender
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-02, Vol.14 (2), p.e0211734
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PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer
Author / Creator:Agarwal, Sumit ; Chakravarthi, Balabhadrapatruni V. S. K. ; Behring, Michael ; Kim, Hyung-Gyoon ; Chandrashekar, Darshan S. ; Gupta, Nirzari ; Bajpai, Prachi ; Elkholy, Amr ; Balasubramanya, Sai A. H. ; Hardy, Cherlene ; Diffalha, Sameer Al ; Varambally, Sooryanarayana ; Manne, Upender
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2020-03, Vol.12 (4), p.772
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Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers

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Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways

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Comparative transcriptome analyses reveal genes associated with SARS-CoV-2 infection of human lung epithelial cells

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Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer

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Global impact of somatic structural variation on the cancer proteome

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Induced Chromosomal Proximity and Gene Fusions in Prostate Cancer

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Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers

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Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

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Author Correction: Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways

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The effect of paclitaxel- and fisetin-loaded PBM nanoparticles on apoptosis and reversal of drug resistance gene ABCG2 in ovarian cancer

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DCZ0415, a small‐molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β‐catenin pathway in colorectal cancer

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Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

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C/EBPβ increases tumor aggressiveness by enhancing KIFC1 expression in androgen receptor negative triple negative breast cancer

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Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression

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Combination of dual JAK/HDAC inhibitor with regorafenib synergistically reduces tumor growth, metastasis, and regorafenib-induced toxicity in colorectal cancer

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Meta-analysis of the robustness of COVID-19 diagnostic kit performance during the early pandemic

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Fermentable fiber-induced hepatocellular carcinoma in mice recapitulates gene signatures found in human liver cancer

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Probabilistic model of the human protein-protein interaction network

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The combined survival effect of codon 72 polymorphisms and p53 somatic mutations in breast cancer depends on race and molecular subtype

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PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer

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