Tau Filaments from Human Brain and from in vitro Assembly of Recombinant Protein Show Cross-β Struct...
Tau Filaments from Human Brain and from in vitro Assembly of Recombinant Protein Show Cross-β Structure
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Abnormal filaments consisting of hyperphosphorylated microtubule-associated protein tau form in the brains of patients with Alzheimer's disease, Down's syndrome, and various dementing tauopathies. In Alzheimer's disease and Down's syndrome, the filaments have two characteristic morphologies referred to as paired helical and straight filaments, wher...
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Full title
Tau Filaments from Human Brain and from in vitro Assembly of Recombinant Protein Show Cross-β Structure
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TN_cdi_proquest_miscellaneous_73477931
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73477931
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1530287100
